منابع مشابه
New Clues in the Malignant Progression of Glioblastoma: Can the Thioredoxin System Play a Role?
AIM To evaluate and compare the expression of thioredoxin reductase 1 (TrxR1) in primary and secondary glioblastoma samples. MATERIAL AND METHODS Surgically resected human glioblastoma samples from 40 patients who underwent surgery at our institution were extracted from their histopathological specimens and divided into three groups. Ten histopathologically regular cerebral tissue samples, ac...
متن کاملMechanisms of malignant progression.
While a coherent picture has begun to emerge about the biological and molecular mechanisms that create primary tumors, the processes that lead subsequently to invasion and metastasis have, until recently, been relatively obscure. However, over the past 5 years, research of diverse sorts has begun to generate the conceptual outlines that explain how high-grade malignancies arise. These discussio...
متن کاملCytotoxic effects of auraptene against a human malignant glioblastoma cell line
Objective: Glioblastoma multiforme (GBM) is the deadliest type of primary brain tumors, and the survival of patients is estimated to be only about one year. This study, for the first time, investigated the cytotoxic effects of auraptene on U87 GBM cell line.<b...
متن کاملMicroRNA-300 inhibited glioblastoma progression through ROCK1
Glioblastoma is a common type of brain aggressive tumors and has a poor prognosis. MicroRNAs (miRNAs) are a class of small, endogenous and non-coding RNAs that play crucial roles in cell proliferation, survival and invasion. Deregulated expression of miR-300 has been studied in a lot of cancers. However, the role of miR-300 in glioblastoma is still unknown. In this study, we demonstrated that m...
متن کاملIdentification and functional characterization of lncRNAs acting as ceRNA involved in the malignant progression of glioblastoma multiforme.
Glioblastoma multiforme (GBM) is the most common brain malignancy. Long non-coding RNAs (lncRNAs) are aber-rantly expressed in many cancers and involved in pathogenesis, progression and metastasis of tumors. In particular, lncRNAs can function as competing endogenous RNAs (ceRNAs). The functional roles of lncRNA associated-ceRNAs in GBM are not fully understood. Human Exon 1.0 Microarray (Affym...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Cell Science & Therapy
سال: 2014
ISSN: 2157-7013
DOI: 10.4172/2157-7013.1000182